So. San Francisco - Industrial Real Estate

Welcome to South San Francisco, a vibrant, industrial gem nestled in the heart of San Mateo County, California. Known affectionately as “The Industrial City,” this dynamic neighborhood offers a unique blend of urban energy and suburban charm. With its rich history rooted in the development of the Bay Area, South San Francisco has evolved into a thriving hub that attracts both businesses and residents alike.

The industrial backbone of the area has fostered a robust economy, making it an ideal location for professionals seeking opportunities in biotechnology, pharmaceuticals, and manufacturing. The presence of industry has not only provided jobs but has also led to the creation of a diverse community, where people from various backgrounds come together to contribute to the local culture.

Beyond its industrial significance, South San Francisco boasts a variety of parks and recreational spaces, perfect for those looking to enjoy the outdoors. The picturesque Sign Hill Park offers stunning views of the city and the Bay, while the nearby Oyster Point Park provides a serene waterfront retreat for picnics and leisurely strolls. The neighborhood is also home to a growing culinary scene, with a range of eateries that reflect the community's diversity, from cozy cafes to eclectic restaurants.

With its convenient access to major highways and proximity to San Francisco, South San Francisco is an ideal location for commuters. Whether you’re seeking a vibrant place to work, a welcoming community to call home, or simply a spot to explore, South San Francisco has something for everyone. Come discover the charm and opportunity that awaits in this remarkable neighborhood!

Newest Listings in So. San Francisco - Industrial

$48,000,000

ML82044309 MLS ⋅ USDA - United States Department BLDG.

MISSION-CRITICAL BIOTECH - FULLY SECURED - FEDERAL TENANT. A premier 21,552 SF high-tech facility purpose-built in 2019. This 3.65-acre site in the heart of the global biotech cluster offers specialized laboratory infrastructure, advanced security, and immediate access to the Bay Areas major transit corridors. The interior features approx. 9,500 SF of professional office, 4,500 SF of mission-critical lab space, and a 7,000 SF warehouse/inspection zone. The build-out includes multiple entomology and botany labs with phenolic resin countertops, 100% ducted exhaust (8 air changes/hour), and high-purity reverse osmosis water systems. A 500kW stand-alone diesel generator and dedicated UPS backup power ensure operational continuity. Logistics are streamlined via 4 interior dock-high doors within a secure devanning area for 53-foot tractor-trailers. This Security Level II facility is fortified with a Lenel card reader system, 24-hour CCTV, shatter-resistant blast-mitigation windows, and a fenced parking area with 62 assigned spaces. With its sophisticated technical build-out and a credit-tenant government lease, this asset represents a rare opportunity in the SSF Life Science submarket. Do not miss this opportunity!

560 Eccles AVE, South San Francisco

Listed by John Tran, 408-931-0897 from KW Elevate
(If provided) CoList: Avi Luzon from Keller Williams Thrive

$499,000

ML82035557 MLS ⋅ Victory Business Center BLDG.

Units 4 and 5 are currently combined via two interior openings: one located within the groundfloor front office area and a second opening on the second floor, also within the office area. Unit 5 features a reception area, a ground-floor office, and a connecting hallway linking Units 4 and 5. The warehouse area includes two ADA-compliant restrooms, a stairwell providing access to the second-floor offices, and a separate staircase leading to the storage mezzanine. The second floor offers four offices, including two located toward the rear above the warehouse-- one with direct access to the mezzanine--and two front-facing offices with windows overlooking the parking lot. An additional hallway on the second floor also connects Units 4 and 5. Wall Opening to Unit 4. Commercial Owners' Association (COA) is $817 a month.

451 Victory AVE 5, South San Francisco

Listed by Stanley Lo, 650-373-0007 from Green Banker Realty
(If provided) CoList: from

$499,000

ML82035565 MLS ⋅ Victory Business Center BLDG.

Units 4 and 5 are currently combined via two interior openings: one located within the groundfloor front office area and a second opening on the second floor, also within the office area. Unit 4 features two ground-floor offices and a connecting hallway linking Units 4 and 5. A rear service room between the office area and warehouse contains two ADA-compliant restrooms and a stairwell providing access to the second floor. The second floor includes a conference room situated above the warehouse, followed by a work area equipped with a garage door opening over the warehouse for convenient forklift access. Two additional offices are located at the front of the second floor, along with another hallway connecting Units 4 and 5. Commercial Owners' Association (COA) is $817 a month.

451 Victory AVE 4, South San Francisco

Listed by Stanley Lo, 650-373-0007 from Green Banker Realty
(If provided) CoList: from

$499,000

ML82035559 MLS ⋅ Victory Business Center BLDG.

Unit 3 encompasses approximately 2,208 square feet and is thoughtfully laid out to support a wide range of industrial and business uses. The space features a prominent front office with an upper-level, providing a professional client-facing presence, complemented by a spacious central warehouse ideal for storage, production, or distribution. A dedicated shipping and receiving area with a 16-foot overhead coiling door allows for efficient loading and logistics. The unit is further enhanced by two ADA-compliant restrooms, offering added convenience for staff and visitors. Commercial Owners' Association (COA) is $817 a month.

451 Victory AVE 3, South San Francisco

Listed by Stanley Lo, 650-373-0007 from Green Banker Realty
(If provided) CoList: from

$6,625,000

CC41080181 MLS

Price improvement! Prime location! This industrial warehouse building is nicely located in the center of South San Francisco. Well maintained approximately 19,800 square feet building is available for Sale or for Lease . Excellent commute location. Conveniently 9 minute to San Francisco Airport. 7 minute to Downtown S.San Francisco. 8 minute to San Bruno BART Station. 14 minute to Cal-Train Station. Easy on and off 101 and 280 freeway. Short drive to San Francisco. Zoning is mixed industrial for variety of uses. There are two warehouse condos with two APN. 12 parking spaces. Two loading docks with one grade level door. Great opening with 19 foot high ceilings. High voltage with a 4000 amp main panel @480/224 volts. Fire Sprinklers. Two ADA compliant restrooms. Nice Office spaces with HAVC recently installed. Excellent opportunity for owner use or for lease. Great potential for owner use and lease portion out for income.

South San

Listed by Anna Li, (510) 853-8810 from Better Homes and Gardens RP
(If provided) CoList: from

Start Your Search

The data relating to real estate for sale on this display comes in part from the Internet Data Exchange program of the MLSListingsTM MLS system. Real estate listings held by brokerage firms other than Intero are marked with the Internet Data Exchange and detailed information about them includes the names of the listing brokers and listing agents.
Based on information from MLSListings MLS as of . All data, including all measurements and calculations of area, is obtained from various sources and has not been, and will not be, verified by broker or MLS. All information should be independently reviewed and verified for accuracy. Properties may or may not be listed by the office/agent presenting the information.